Matches in Nanopublications for { ?s ?p <https://doi.org/10.1021/acs.biomac.1c01274> ?g. }
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- Compared%20with%20the%20unmodified%20nanoparticles%20which%20exhibited%20the%20smallest%20size%20%28188%20nm%29%2C%20all%20three%20surface%20modified%20formulations%20showed%20significantly%20larger%20sizes%20%28i.e.%2C%20222%E2%88%92277%20nm%29. obtainsSupportFrom acs.biomac.1c01274 assertion.
- Under%20simulations%20of%20biofilm%20pH%20conditions%2C%20the%20mannose%20modified%20nanoparticle%20%28PDM%2090%2F5%2F5%29%20displayed%20ideal%20charge%20reversal%20from%20a%20neutral%20%28%2B1.69%20%C2%B1%201.83%20mV%29%20to%20a%20cationic%20surface%20potential%20%28%2B17.18%20%C2%B1%202.16%20mV%29%20to%20improve%20bacteria%20binding%20and%20biofilm%20penetration. obtainsSupportFrom acs.biomac.1c01274 assertion.
- In%20the%20presence%20of%20relevant%20bacterial%20enzymes%2C%20the%20carrier%20rapidly%20released%20the%20DNA%20nanoparticles%20to%20function%20as%20an%20antitoxin%20against%20%CE%B1-hemolysin. obtainsSupportFrom acs.biomac.1c01274 assertion.
- Controlled%20release%20of%20vancomycin%20prevented%20biofilm%20attachment%20and%20significantly%20reduced%20early%20stage%20biofilm%20formations%20within%2024%20h. obtainsSupportFrom acs.biomac.1c01274 assertion.
- Enhanced%20biocompatibility%20and%20significant%20ex%20vivo%20potency%20of%20the%20PDM%2090%2F5%2F5%20formulation%20was%20also%20observed. obtainsSupportFrom acs.biomac.1c01274 assertion.
- The%20entrapment%20efficiency%20of%20vancomycin%20in%20the%20PD%20formulation%20was%2067.8%20%C2%B1%203.39%25%2C%20and%20there%20was%20no%20significant%20difference%20observed%20between%20the%20PD%20formulation%20and%20the%20PDM%20formulation%20%2868.05%20%C2%B1%204.45%25%29. obtainsSupportFrom acs.biomac.1c01274 assertion.
- Exposure%20to%2050%20%CE%BCg%2FmL%20of%20PDM%2090%2F5%2F5%20formulation%20resulted%20in%20cellular%20viability%20exceeding%2080%25%20%28i.e.%2C%2086.57%20%C2%B1%203.79%25%29. obtainsSupportFrom acs.biomac.1c01274 assertion.
- A%20significant%20reduction%20in%20fluorescence%20intensity%20%2817124%20%C2%B1%20884.6%29%20on%20the%20skin%20sections%20was%20observed%20after%20the%20PDM%2090%2F5%2F5%20formulation%20was%20topically%20applied%20to%20the%20mature%20biofilms. obtainsSupportFrom acs.biomac.1c01274 assertion.