Matches in Nanopublications for { ?s ?p ?o <http://purl.org/np/RAG9k5BaQM7A3ZJyiXeXWNDSwTvTKre8lI_ewAcXflV9A#assertion>. }
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- DB00656 type Drug assertion.
- MONDO_0100081 type Disease assertion.
- context type Cohort assertion.
- association type ChemicalToDiseaseOrPhenotypicFeatureAssociation assertion.
- DB00656 label "Trazodone" assertion.
- MONDO_0100081 label "sleep disorder" assertion.
- context label "Adults" assertion.
- association label "Among TCAs, doxepin (sinequan) appears to be best suited for managing insomnia in healthy adults. Doxepin works as a selective antagonist to H(1) receptors, which promote the initiation and maintenance of sleep (Owen, 2009) (Table 2 contains information on trazodone and mirtazapine). Ultra-low doses of this drug (< 6 mg per day) significantly improve and sustain both maintenance and duration of sleep (Rojas-Fernandez and Chen, 2014; Weber et al., 2010). Another frequently prescribed TCA is amitriptyline, which as a long-term option is found to be effective for patients with ongoing sleep problems (Everitt et al., 2014; Pagel and Parnes, 2001)." assertion.
- association subject DB00656 assertion.
- association predicate treats assertion.
- association object MONDO_0100081 assertion.
- association has_population_context context assertion.
- association relation NCIT_C94303 assertion.
- DB00656 category Drug assertion.
- MONDO_0100081 category Disease assertion.
- context category Cohort assertion.
- association category ChemicalToDiseaseOrPhenotypicFeatureAssociation assertion.
- association publications 31622593 assertion.
- association aggregator_knowledge_source knowledge-collaboratory assertion.